Selected Issues from Biomaterials Toxicology Field of study: Biophysics
Programme code: W4-S2BFA21.2021

Module name: Selected Issues from Biomaterials Toxicology
Module code: W4-2BF-MB-21-28
Programme code: W4-S2BFA21.2021
Semester: winter semester 2022/2023
Language of instruction: English
Form of verification: exam
ECTS credits: 2
Description:
This course will provide students with the issues related to biomaterials toxicology, including terms and definitions such as: toxin (poison), toxicity, degrees of toxicity, types of intoxications, adsorption of toxic substances and biocorrosion. The module shall ensure that students are knowledgeable about toxic action mechanisms and dynamics, based on which students shall understand the importance of biomaterials toxicity and its adverse effects of impact on the organism. Program: laboratory 1. Organization of classes. 2. Ways of distributing harmful compounds to the body. The effect of drugs on the presence of an implant in the body. The effect of alcohol on the presence of the implant in the body. 3. Effect of drugs on the presence of the implant in the body. Toxicity of metals found in titanium-containing biomaterials additives. Toxicity of metals present in 316L implant steel. 4. Diseases caused by the presence of metals in food. Toxicity of ceramic implants. Life expectancy of implants. 5. Toxicological assessment of cosmetic raw materials. Toxicity of plastics. Methods for determining metals in the material biological. 6. Methods of neutralizing poisons. Toxicity of metals and semimetals. 7. Toxicity of non-metals and their inorganic compounds. Toxicity of addictive substances (hallucinogens). 8. Written test / test. Program: lecture 1. Toxin (poison), toxicity, degrees of toxicity, types of poisoning. 2. Mechanisms of toxic action. 3. Adsorption of toxic substances. 4. Metabolic disorders caused by poisons. 5. Morphological disorders caused by poisons. 6. The carcinogenic response of a living organism to the implant. 7. Allergic reaction of the living organism to the implant. 8. Allergy mechanisms. 9. Allergies caused by implants. 10. Infection mechanisms caused by implanted materials. 11. Biocorrosion.
Prerequisites:
(no information given)
Key reading:
(no information given)
Learning outcome of the module Codes of the learning outcomes of the programme to which the learning outcome of the module is related [level of competence: scale 1-5]
Understands the relationship between material properties and basic laws of nature [MB_28_1]
 KBF_W01 [4/5] KBF_W02 [4/5]
Acquired basic knowledge about theoretical specification of material properties (specific heat, susceptibility etc.) [MB_28_2]
 KBF_W02 [4/5]
Analyses of various type computational approximations [MB_28_3]
 KBF_U02 [4/5]
Acquired the knowledge about materials electron structure, magnetism, dielectric and other properties [MB_28_4]
 KBF_W01 [4/5] KBF_W02 [4/5]
Acquired the skill to resolve theoretical problems from the field of material properties computation [MB_28_5]
 KBF_U02 [4/5] KBF_U09 [4/5]
Acquired the skill to apply specified computational methods and approximations [MB_28_6]
 KBF_U02 [4/5] KBF_U05 [4/5] KBF_U06 [4/5]
Analyses of various type approaches to theoretical determination of material properties [MB_28_7]
 KBF_U02 [4/5] KBF_K10 [4/5]
Type Description Codes of the learning outcomes of the module to which assessment is related
exam [MB_28_w_1]
Verification of knowledge based on the content of the lectures, the indicated literature and the auditorium exercises
 MB_28_1 MB_28_2 MB_28_3 MB_28_4
credit [MB_28_w_2]
Verification of the knowledge acquired during the auditorium exercises
 MB_28_5 MB_28_6 MB_28_7
Form of teaching Student's own work Assessment of the learning outcomes
Type Description (including teaching methods) Number of hours Description Number of hours
lecture [MB_28_fs_1]
Detailed discussion by the lecturer of the issues listed in the table "module description". The lecture is conducted with the use of multimedia resources, based on a selected set of textbooks.
 30
Work with the selected literature including the independent acquisition of knowledge in relation to the issues covered in the lectures.
 10 exam [MB_28_w_1]
laboratory classes [MB_28_fs_2]
Based on the discussion and problem solving with the use of multimedia.
 15
Preparation for exercises through self study of the indicated issues.
 5 credit [MB_28_w_2]
Attachments
Module description (PDF)
Information concerning module syllabuses might be changed during studies.
Syllabuses (USOSweb)
Semester Module Language of instruction
(no information given)