Biophysical and Materials Science Characterization Field of study: Biophysics
Programme code: W4-S2BFA21.2022

Module name: Biophysical and Materials Science Characterization
Module code: W4-2BF-MB-21-14
Programme code: W4-S2BFA21.2022
Semester:
  • summer semester 2024/2025
  • summer semester 2023/2024
  • summer semester 2022/2023
Language of instruction: English
Form of verification: exam
ECTS credits: 4
Description:
The course aims to provide an introduction to chemical physics, especially on liquid solutions (both electrolyte and nonelectrolyte), solid solutions, and homogeneous and hybrid materials, and on the relevant characterization techniques. Course syllabus: (1) Introduction to inorganic chemical physics of electrolyte & nonelectrolyte solutions Types of solutions. Thermodynamics of solutions. Properties of water: The hydrogen bond, solubility of molecules in water, polar and non-polar solvents. Electrical permeability of water. Dissociation: acids and bases, protonation. Properties of solutions: functional groups, hydrophilic and hydrophobic interactions; solubility; diffusion. Colligative properties: boiling-point elevation, freezing point depression, osmotic pressure. Surface tension, capillarity. Water phase diagram and anomalies; aqueous electrolytes; non-electrolyte solutions. Electrostatics of salty solutions: biopolymers (polyelectrolytes) and biomembranes in water; Poisson-Boltzmann equation, Debye-Hückel model, electric double layers, ion, and proton conduction; transport properties. (2) Introduction to materials science properties Cohesive interactions; structural and mechanical properties of homogeneous solids; organic molecular solids; non-miscible systems: morphology and properties of phase-separated materials (3) Laboratory techniques - Elemental analysis: photoelectron & mass spectroscopy (XPS, UPS, Auger, secondary ion mass spectroscopy) - Chemical analysis: optical and vibrational spectroscopy (UV-vis, IR, Raman), nuclear magnetic resonance (NMR) - Morphological analysis: contact angle, powder X-ray diffraction (XRD), tomography (microCT), NMR-imaging, electron microscopy (SEM, TEM, energy loss/secondary electron spectroscopy) - Phase-change analysis - Mechanical, electrical, and optical characterization - A pharmaceutical application: optical measurement of the dissolution kinetics and solubility of a drug (4) Applications to pharmaceutics, drug formulation, & biophysical pharmacology: - Experimental techniques for electrolyte and non-electrolyte solutions - Small Molecules (drugs): HPLC, Chromatography, Mass spectroscopy, ICP-MS - Characterization of Nanoparticles: Molecular sizes (Dynamics light scattering, DLS), Surface charge (zeta potential, with conductivity measures) - Characterization of Biomolecules: chromatography, gel electrophoresis, Western Blot. Proteomics
Prerequisites:
(no information given)
Key reading:
(no information given)
Learning outcome of the module Codes of the learning outcomes of the programme to which the learning outcome of the module is related [level of competence: scale 1-5]
students will be able to understand and describe the fundamental properties of aqueous solutions and complex materials [MB_14_1]
 KBF_W02 [4/5] KBF_W07 [4/5] KBF_U03 [4/5] KBF_U08 [4/5]
students will be able to describe the application of experimental physicochemical methods to the solid and liquid states and choose the appropriate experimental techniques that serve a specific purpose [MB_14_2]
 KBF_W02 [4/5] KBF_W10 [4/5] KBF_U01 [3/5] KBF_U09 [3/5]
Type Description Codes of the learning outcomes of the module to which assessment is related
credit [MB_14_w_1]
the basis for obtaining credit will be the grades from homework and laboratory reports
 MB_14_1 MB_14_2
exam [MB_14_w_2]
oral/written exam
 MB_14_1 MB_14_2
Form of teaching Student's own work Assessment of the learning outcomes
Type Description (including teaching methods) Number of hours Description Number of hours
lecture [MB_14_fs_1]
Detailed discussion by the lecturer of the issues listed in the table "module description" using the table and/or multimedia presentations
 30
Supplementary reading, working with the textbook, doing homework
 44 exam [MB_14_w_2]
laboratory classes [MB_14_fs_2]
Performance of exercises on the subject consistent with the issues listed in the table "module description"
 6
Acquiring knowledge in the scope of the exercise, preparation of the final report on a given exercise
 20 credit [MB_14_w_1]
Attachments
Module description (PDF)
Information concerning module syllabuses might be changed during studies.
Syllabuses (USOSweb)
Semester Module Language of instruction
(no information given)