Molecular Biophysics Field of study: Biophysics
Programme code: W4-S2BFA21.2021

Module name: Molecular Biophysics
Module code: W4-2BF-MB-21-20
Programme code: W4-S2BFA21.2021
Semester: winter semester 2022/2023
Language of instruction: English
Form of verification: exam
ECTS credits: 5
Description:
By participating in the classes, the student will deepen their knowledge in the field of biophysics by performing research on various biological objects, from single molecules, through subcellular complexes and structures, to the structures of living matter using methodology and physics methods. It will be an opportunity to understand the basics of many advanced research techniques and take part in experiments performed using them. Familiarize yourself with, among others with the following research methods: 1) Spectroscopy and fluorescence microscopy used to observe the structure and follow cell life processes. 2) Multidimensional nuclear magnetic resonance (NMR) in imaging of tissue structure and observation of cellular changes. 3) Atomic force microscopy (AFM) in the study of individual molecules, forces of interaction between them and the structure of molecular and cellular systems as well as characteristics of their mechanical (viscoelastic) properties. 4) Microscale Raman spectroscopy - Raman mapping and surface enhanced Raman spectroscopy (SERS). 5) Electron cryomicroscopy of single molecules and molecular systems. 6) Mass spectrometry in the study of the atomic and molecular composition of substances and tissues (ToF-SIMS). 7) Analytical centrifugation. 8) Theoretical methods for modeling the structure, spectra and properties of molecules and their systems - the use of molecular dynamics and ab-initio modeling methods.
Prerequisites:
(no information given)
Key reading:
(no information given)
Learning outcome of the module Codes of the learning outcomes of the programme to which the learning outcome of the module is related [level of competence: scale 1-5]
The student understands the physical basis of known research techniques used in molecular biophysics [MB_20_1]
 KBF_W01 [4/5] KBF_W02 [4/5] KBF_U03 [4/5] KBF_K07 [4/5]
The student can characterize and develop the results of research obtained for biological systems [MB_20_2]
 KBF_W02 [3/5] KBF_W03 [3/5] KBF_K05 [3/5]
The student knows the principles of operation, capabilities and specificity of high-class research equipment [MB_20_3]
 KBF_W02 [3/5] KBF_W04 [3/5] KBF_W08 [3/5] KBF_U03 [3/5] KBF_K03 [3/5]
The student knows how to use mathematical and statistical methods of developing experimental results [MB_20_4]
 KBF_W02 [3/5] KBF_W04 [3/5] KBF_K09 [3/5]
Student through acquired knowledge from physics and biology knows how to propose a method of research of various biological systems, thanks to which he becomes a natural partner of biologists and doctors [MB_20_5]
 KBF_W02 [3/5] KBF_W03 [3/5] KBF_U07 [3/5] KBF_U08 [3/5] KBF_K03 [3/5]
Type Description Codes of the learning outcomes of the module to which assessment is related
exam [MB_20_w_1]
Written exam/oral exam. The scope of the exam will be announced 3 weeks before the end of the semester
 MB_20_1 MB_20_2 MB_20_3 MB_20_4 MB_20_5
credit [MB_20_w_2]
Passing the preliminary test before each new exercise, performing the exercise, preparing a report
 MB_20_1 MB_20_2 MB_20_3 MB_20_4 MB_20_5
Form of teaching Student's own work Assessment of the learning outcomes
Type Description (including teaching methods) Number of hours Description Number of hours
lecture [MB_20_fs_1]
Detailed discussion by the lecturer of the issues listed in the table "module description" using the table and/or multimedia presentations
 15
Supplementary reading, working with the textbook, trying to find answers to simple problem questions asked during the lecture
 20 exam [MB_20_w_1]
laboratory classes [MB_20_fs_2]
Performance of exercises on professional research equipment
 30
Acquiring knowledge in the scope of the exercise. Preparation of the final report on a given exercise
 45 credit [MB_20_w_2]
Attachments
Module description (PDF)
Information concerning module syllabuses might be changed during studies.
Syllabuses (USOSweb)
Semester Module Language of instruction
(no information given)